Research highlights the discovery of new bioactive compounds in coffee that may aid in diabetes management. These findings showcase advanced techniques to identify beneficial components in complex food matrices.
• Scientists used a three-step strategy to identify bioactive diterpene esters in roasted coffee beans.
• The study focused on compounds with α-glucosidase inhibitory activity, which can help regulate blood sugar levels.
• Advanced methods like NMR and LC-MS/MS were employed to minimize time and solvent use during analysis.
• Three new compounds, caffaldehydes A, B, and C, were isolated and showed promising activity, outperforming a common diabetes medication.
Understanding these compounds is crucial as they may lead to new functional food ingredients aimed at managing diabetes. The techniques developed can be applied to other foods, speeding up the discovery of health-promoting compounds. This research could have a significant impact on nutrition and health, paving the way for innovative dietary solutions.
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