Caffeine may hold the key to longevity and cellular health, according to recent research from Queen Mary University of London. The study examined how caffeine affects aging, DNA repair, and cellular stress responses using fission yeast, a single-celled organism similar to human cells. Researchers discovered that while caffeine can extend lifespan, it also has complex effects on how cells manage stress and DNA damage.
• Caffeine activates AMPK, a cellular energy regulator, which influences growth and repair processes in cells.
• The study found that caffeine can amplify DNA damage instead of protecting it, allowing damaged cells to continue dividing.
• Benefits of caffeine depend on specific proteins and pathways, explaining mixed results in past health studies.
• Previous research shows coffee drinkers may enjoy lower mortality rates and a reduced risk of diseases like Alzheimer’s and Parkinson’s.
Understanding caffeine's dual effects is crucial for future health strategies. While it may enhance longevity, its impact on DNA repair raises questions about its long-term effects. This research opens avenues for exploring how diet and lifestyle can harness caffeine's benefits while minimizing risks.
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